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CA 15-3

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Diğer Adları: CA-Meme; Kanser antijen-meme
Resmi adı: Kanser Antijen 15-3

Bir Bakışta

Niçin Testi Yaptıracaksınız?

İnvaziv meme kanserinin tedavisine yanıtı izlemek ve hastalık nüksünü gözlemek için bu test yapılır.

Ne Zaman Testi Yaptıracaksınız?

İnvaziv meme kanseri için tedavi edilmiş veya edilmekte olduğunuz zaman bu test yapılr.

Gerekli Numune Nedir?

Kolunuzun bir damarından kan alınır.

Test için Hazırlık Gerekir mi?

Test için hazırlık yapılması gerekmemektedir.

Test Numunesi

Ne test edilmektedir?

Kanser antijeni 15-3 (CA 15-3) normal meme hücreleri tarafından üretilen bir proteindir. Kanserli meme tümörleri olan birçok hastada CA 15-3  ve ilişkili kanser antijeni 27.29'un üretimi artmıştır. CA 15-3 kansere neden olmamakta daha çok tümör hücreleri tarafından saçılmakta, kan dolaşımına girerek kanser seyrini takipte yararlı bir tümör belirtecine dönüşmektedir.  Erken lokalize meme kanseri olan kadınların yaklaşık % 10'u ve metastatik meme kanseri olanların ise % 70'inde CA 15-3 yükselmektedir. CA 15-3  ayrıca sağlıklı kişilerde, kolorektal kanser, akciğer kanseri, siroz, hepatit, ve iyi huylu meme hastalığı gibi kanser, rahatsızlıklar veya hastalıklar olanlarda da yükselebilmektedir.

Test için numune nasıl toplanır?

Bir kol damarından iğneyle alınan kan numuneleri kullanılır.

Numunenin kalitesinden emin olmak için herhangi bir test hazırlığına gerek var mı?

Test için hazırlık yapılması gerekmemektedir.

Test

Sık Sorulan Sorular

Bir Laboratuvar Uzmanına Sorun

* doldurulması gerekli alanı gösterir



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Makalenin Kaynakları

« İlgili Sayfalara Geri dönün

NOT: Bu makale, burada söz edilen kaynaklarla birlikte Lab Tests Online Editörler İnceleme Kurulunun toplu deneyiminden yararlanan araştırmaya dayanmaktadır. Bu makale belli aralıklarla Editörler Kurulu tarafından gözden geçirilmekte ve inceleme sonuçlarına göre güncelleştirilebilmektedir. Alıntı yapılan her yeni kaynak listeye eklenecek ve kullanılan orijinal kaynaklardan ayırt edilecektir.

En son gözden geçirmede kullanılan kaynaklar

Pagana, K. D. & Pagana, T. J. (© 2007). Mosby's Diagnostic and Laboratory Test Reference 8th Edition: Mosby, Inc., Saint Louis, MO. Pp 214-215.

Clarke, W. and Dufour, D. R., Editors (© 2006). Contemporary Practice in Clinical Chemistry: AACC Press, Washington, DC. Pp 247.

Wu, A. (© 2006). Tietz Clinical Guide to Laboratory Tests, 4th Edition: Saunders Elsevier, St. Louis, MO. Pp 206-207.

(Revised 2008 December 08). Tumor Markers. American Cancer Society [On-line information]. Available online at http://www.cancer.org/docroot/PED/content/PED_2_3X_Tumor_Markers.asp?sitearea=PED through http://www.cancer.org. Accessed August 2009.

(Updated 2009 May) Tumor Markers. ARUP Consult [On-line information]. Available online at http://www.arupconsult.com/resources/print/TumorMarkers.pdf through http://www.arupconsult.com. Accessed August 2009.

Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. Burtis CA, Ashwood ER and Bruns DE, eds. 4th ed. St. Louis, Missouri: Elsevier Saunders; 2006, Pp 770-771.

Park, B et al. Preoperative CA 15-3 and CEA serum levels as predictor for breast cancer outcomes. Annals of Oncology 2008 19(4):675-681. Available online at http://annonc.oxfordjournals.org/cgi/content/full/19/4/675 through http://annonc.oxfordjournals.org. Accessed September 2009.

Daha önceki gözden geçirmede kullanılan kaynaklar

Thomas, Clayton L., Editor (1997). Taber's Cyclopedic Medical Dictionary. F.A. Davis Company, Philadelphia, PA [18th Edition].

Pagana, Kathleen D. & Pagana, Timothy J. (2001). Mosby's Diagnostic and Laboratory Test Reference 5th Edition: Mosby, Inc., Saint Louis, MO.

Check, W. (1998 July) Reaching agreement on tumor markers. CAP Today, In the News [On-line journal]. Available online at http://www.cap.org/captoday/archive/1998/julycover.html through http://www.cap.org.

NCI (1998 April 27). Tumor markers. National Cancer Institute, Cancer Facts [On-line information]. Available online at http://cis.nci.nih.gov/fact/5_18.htm through http://cis.nci.nih.gov.

ACS (2000 July 19). Tumor Markers. American Cancer Society, Prevention and Early Detection [On-line information]. Available online through http://www.cancer.org.

AACC (2001 July 27) Use of Tumor Markers in Cancer Patients Leads to Better Detection, Decreasing Mortality. AACC Media Center, American Association for Clinical Chemistry [On-line press release]. PDF available for download at http://www.aacc.org/media/TumorMarkers.pdf through http://www.aacc.org.

ASCO (1996 May 17, adopted, revision every 3 years). CA 15-3 as a Marker for Breast Cancer. American Society for Clinical Oncologists, Clinical Practice Guidelines for the Use of Tumor Markers in Breast and Colorectal Cancer [On-line guidelines]. Available online at http://www.asco.org/prof/pp/html/guide/tumor/m_tumor10.htm through http://www.asco.org.

Merck (2000). Cancer and the Immune System. The Merck Manual of Medical Information Home Edition, Section 15 Cancer, Ch 163 [On-line information]. Available online at http://www.merck.com/pubs/mmanual_home/sec15/163.htm through http://www.merck.com.

Duffy, M. (1999). CA 15-3 and related mucins as circulating markers in breast cancer. Ann Clin Biochem [On-line journal]. Vol 36: 579-586. PDF available for download at http://www.leeds.ac.uk/acb/annals/annals_pdf/Sept%2099/ACB579.PDF through http://www.leeds.ac.uk.

Srirangam, S. and Harland, R. (2001). Management of Advanced Breast Cancer. Forum for Registrars In Surgical Training [On-line information]. PDF available for download at http://www.frist.org/asit/meetings/yearbook2001/BREAST%20CANCER.pdf through http://www.frist.org.